![]() The localization of β-glucuronidase activity in the adrenals of patients with or without cancer was similar, but the number and intensity of areas with β-glucuronidase activity was decreased in the adrenals from cancer patients. The distribution of cell groups with β-glucuronidase activity was patchy. Histochemically, the highest β-glucuronidase activity was localized in the zona glomerulosa in over 50% of cases the other cortical layers or the medulla showed the highest activity in the remaining cases. Several cancer patients were treated with corticoids this treatment was without effect on the adrenal β-glucuronidase concentration. The patient's age appeared to be without effect on the adrenal β-glucuronidase concentration an influence of the nutritional status independently of the disease could not be evaluated. The mean β-glucuronidase concentration in the adrenal homogenate of male patients with cancer was found to be significantly lower than that of male patients without cancer. ![]()
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